The European Commission has published a new study highlighting the contribution of Horizon Europe to excellent science across the Framework Programme (FP), with a particular focus on activities under Pillar 1, Excellent Science – namely, the European Research Council (ERC), the Marie Skłodowska-Curie Actions (MSCA), and Research Infrastructures (INFRA), including the European Open Science Cloud (EOSC) Partnership, as well as activities under the horizontal pillar on Widening Participation and Strengthening the European Research Area (WIDERA). The study is part of the mid-term evaluation of Horizon Europe, the EU Framework Programme for Research and Innovation for 2021-2027.